|
KMID : 0363620090300050146
|
|
Journal of Korean Oriental Medicine
2009 Volume.30 No. 5 p.146 ~ p.156
|
|
|
Antioxidative Activities of Wen-pi-tang-Hab-Wu-ling-san (WHW) in vitro
|
|
Jung Jin-Ki
Park Yong-Ki
|
|
|
Abstract
|
|
|
Objectives: The objective of this study was to investigate the antioxidant effects of manufactured Wen-pi-tang-Hab-Wu-ling-san (WHW) in vitro.
Methods: WHW was prepared by the pilot manufacture of WHW water extract from a GMP system appointed company. Antioxidative activities were determined by in vitro tests as follows: the scavenging activities of oxygen free radicals including 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, superoxide anion, hydrogen peroxide and nitric oxide radicals, as well as ferrous ion chelating capacity and Trolox equivalent antioxidant capacity (TEAC).
Results: WHW significantly scavenged oxygen free radicals such as DPPH (IC=115.28 0.25 g/), superoxide anion (IC=8.56 0.08 g/), hydrogen peroxide (IC=240.36 3.41 g/) and nitric oxide (IC=162.28 0.21 g/) radicals. WHW also showed ferrous ion chelating activity (IC=543.19 4.85 g/) and Trolox equivalent effects (IC=45.311 g/) in TEAC and ORAC assay, respectively.
Conclusion: This study demonstrates that WHW has strong antioxidative properties through free radical scavenging activity. These data suggest that WHW be used as an antioxidant agent.
|
|
|
KEYWORD
|
|
|
Traditional Korean medicine, Wen-pi-tang-Hab-Wu-ling-san, antioxidation, free radicals
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|